TRANSIL® RSA Binding
Kit
A ready-to-use kit for rapid
assessment of drug candidates' binding to rat serum albumin
(RSA)
A novel ready-to-use binding kit designed to assess the
binding of drugs to rat serum albumin (RSA). The affinity of
a drug candidate to plasma proteins is a true measurement of
the free fraction of a drug candidate in plasma.
Benefits
- Fast, requiring only 2 minutes for
incubation.
- Accurate. Measures the affinity of
the drug candidate to rat serum albumin (RSA), a
true measurement of the free fraction in plasma,
capable of producing pharmacological effects.
- Reliable with highly reproducible
results, and robust correlation to the gold
standard equilibrium dialysis method (end-point
measurement). Fully quality-controlled plasma
protein binding estimates.
- Ready-to-use format plated in 96-well
or ready-to-use tubes in strips of 8. Kit
requires only addition of test material,
2-minute incubation, and quantification.
- Flexible. Enables physiology based
modeling (e.g Simcyp) by providing affinity
input data. Format is adaptable to automation.
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Product Information
Product Number |
Product Name |
Format |
TPB-0220-0096 |
Transil®
RSA Binding Kit |
96-well
plate |
TPB-0220-1196 |
Transil®
RSA Binding Kit |
96-well
(strips) |
|
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