TRANSIL^® HSA Binding Kit

A ready-to-use kit for rapid assessment of drug candidates' binding to human serum albumin (HSA)

A novel ready-to-use binding kit designed to assess the binding of drugs to plasma binding protein, and mimics the physiological condition of the major plasma protein human serum albumin (HSA). The affinity of a drug candidate to plasma proteins is a true measurement of the free fraction of a drug candidate in plasma, as the free fraction is only meaningful when relating a compound’s affinity to its receptor with its affinity to the plasma proteins.

Benefits

Fast, requiring only 2 minutes for incubation.
Accurate. Measures the affinity of the drug candidate to human serum albumin (HSA), a true measurement of the free fraction in plasma, capable of producing pharmacological effects.
Reliable with highly reproducible results, and robust correlation to equilibrium dialysis method (end-point measurement). Fully quality-controlled albumin binding estimates.
Ready-to-use format plated in 96-well or ready-to-use tubes in strips of 8. Kit only requires addition of test material, 2-minute incubation, and quantification.
Flexible. Enables physiology based modeling (e.g Simcyp) by providing affinity input data. Format is adaptable to automation.

Product Information

Product Number	Product Name	Format
TPB-0210-0096	Transil^® HSA Binding Kit	96-well plate
TPB-0210-1196	Transil^® HSA Binding Kit	96-well (strips)

TRANSIL® HSA Binding Kit

Benefits

Product Information

TRANSIL^® HSA Binding Kit